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Journal of Craniovertebral Junction and Spine
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Year : 2020  |  Volume : 11  |  Issue : 4  |  Page : 249-251  

When is inclusion of C2 vertebra in the fixation construct necessary in cases with multi-level spinal degeneration?

Department of Neurosurgery, King Edward VII Memorial Hospital and Seth G.S. Medical College, Mumbai, Maharashtra, India

Date of Submission04-Oct-2020
Date of Acceptance11-Oct-2020
Date of Web Publication26-Nov-2020

Correspondence Address:
Atul Goel
Department of Neurosurgery, King Edward VII Memorial Hospital and Seth G.S. Medical College, Parel, Mumbai - 400 012, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jcvjs.JCVJS_167_20

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How to cite this article:
Goel A. When is inclusion of C2 vertebra in the fixation construct necessary in cases with multi-level spinal degeneration?. J Craniovert Jun Spine 2020;11:249-51

How to cite this URL:
Goel A. When is inclusion of C2 vertebra in the fixation construct necessary in cases with multi-level spinal degeneration?. J Craniovert Jun Spine [serial online] 2020 [cited 2022 May 25];11:249-51. Available from: https://www.jcvjs.com/text.asp?2020/11/4/249/301628

Instability is the cause, and stabilization is the treatment for single-or multi-level spinal degeneration. Our several articles refer to this issue and suggest that for patients presenting with cervical radiculopathy or myelopathy in cases with single-or multi-level spinal degeneration with or without ossification of posterior longitudinal ligament (OPLL) decompression by removal of bone, ligament, disc or bone component of OPLL is unnecessary and “only-stabilization” is the treatment.[1],[2],[3],[4],[5],[6],[7],[8],[9],[10],[11],[12],[13],[14],[15],[16],[17],[18] Our hypothesis is based on the concept that weakness of the muscles of the back of the spine, particularly those involved in maintaining standing human posture, leads to “vertical” spinal instability that is first manifested at the facets in the form of listhesis of the inferior facet of the rostral vertebral over the superior facet of the caudal vertebra.[15] Due to the subtle nature of dislocation and lateral location of the facets that is away from neural structures, radiological identification of instability or dislocation is difficult or impossible.[19] Our studies conclude that the term “spinal canal stenosis” is a misnomer and directs to erroneous treatment and should be changed to single- or multi-level “spinal instability.”[20] Spinal instability is also a primary issue in cases with prolapsed and herniated disc. The instability is either the cause of disc herniation or disc herniation leads to spinal instability. Essentially, our hypothesis suggests that spinal instability is the primary issue and all the so-called “pathological alterations” are secondary in nature and “protective” in function.

Buckling of the interspinous ligaments that include ligamentum flavum and OPLL, osteophyte formation, reduction of the intervertebral disc space and all the other known pathological features of degenerative spondylosis are secondary consequences of vertical spinal instability. Essentially, these secondary features are radiological musculoskeletal evidence of spinal instability. The net effect is reduction in the spinal and neural canal dimensions. Radiating pain, weakness, or paresthesiae in affected dermatomes are clinical evidence of the level of spinal instability. Radiological evidence of neural compression indicate subtle, manifest, or potential spinal instability even in the absence of clinical manifestations. On the other hand, clinical features, even in the absence of radiological evidence can suggest spinal instability and indicate the need for surgical treatment. Spinal medullary cord changes without any compressive neural factor indicate vertical spinal instability and longitudinal buckling of the spinal cord. The cause of symptoms is spinal instability and not physical neural compression.[18] It is important to note that there may be spinal instability even in the absence of clinical and/or radiological evidence. Ignoring neighboring unstable spinal segments and treatment of only the spinal level having radiological evidence is an important cause of the surgical failure or delayed “adjacent segment disease.” Spinal stabilization is usually necessary in more segments than that demonstrated by radiological images and evidence of neural compression and clinical parameters.

Atlantoaxial joint is the most mobile joint of the body and is the most likely joint to develop spinal instability. Our studies suggest that atlantoaxial instability has been traditionally ignored as a likely site for spinal degeneration. Significant or severe symptoms related to cervical myelopathy are more often than not associated with atlantoaxial instability. Atlantoaxial instability is generally associated in cases with multi-level spinal degeneration that is more often seen in “old-age” patients.[12],[13] Atlantoaxial instability can be present even without any neural compression in the region or any radiological evidence of spinal instability on dynamic imaging.

Direct inspection of the facetal articulation by exposing the segments in the vicinity of those suggested by clinical and radiological guides is crucial to identify the unstable spinal levels. Excessive or abnormal movements on spinal manipulation, identification of osteophytes in the proximity of facets, and unusually open articular cavity can indicate spinal instability.

Our recent classification divides atlantoaxial instability into three types depending on the facetal alignment on lateral profile imaging with the head in neutral position.[21] Type 1 atlantoaxial instability is when the facet of atlas is dislocated anterior to the facet. Type 2 atlantoaxial instability is when the facet of atlas is dislocated posterior to the facet of axis. Type 3 atlantoaxial instability is when the facets of atlas and axis are in alignment and atlantoaxial instability is diagnosed based on corroborative evidence. As there may not be any atlantodental interval disturbance and there may not be any neural or dural compression adjacent to the odontoid process, Types 2 and 3 atlantoaxial instability are referred to as central or axial atlantoaxial instability.[21] Such central atlantoaxial dislocation is usually associated with chronic or longstanding instability. Direct observation of the facetal articulation and excessive or abnormal movements of the joint on bone manipulation is the final or confirmatory evidence of atlantoaxial instability. Essentially it means that there can be atlantoaxial instability even in the absence of any evidence of bone abnormality or any kind of neural compression. Multi-level spinal degeneration is more often associated with central or axial atlantoaxial instability.

Direct facetal fixation is biomechanically the most stable as it fixes the point of fulcrum of spinal movements. For subaxial spine, Camille's technique of transarticular fixation is quick, safe, strong and relatively “easy.”[22] Two or even three transarticular screw insertion is possible to provide “double-insurance” or “triple insurance” fixation. Goel technique of atlantoaxial fixation has been identified to be biomechanically the most stable fixation technique.[23],[24] Recently, we described an alternative atlantoaxial fixation technique by fixing C2-3 articulation by transarticular fixation and sectioning the muscles attached to the C2 spinous process.[25] The technique disables movements of the odontoid process and retains transverse or rotatory movements executed by the muscles attached to the transverse process of the atlas. Even though direct atlantoaxial fixation, as described in our technique is an ideal form of surgical treatment in cases with multi-level cervical spinal degeneration, the alternative fixation technique can be used as an option as it preserves rotatory neck movements.

Inclusion of the C2 spinal segment in the fixation construct with the aim to provide selective atlantoaxial stabilization is crucial and mandatory in a “large” number of cases with multi-level spinal degeneration. Such stabilization is particularly essential in cases where the myelopathy is moderately or significantly severe and in old age patients. Ignorance of association of atlantoaxial instability and ignoring the inclusion of the C2 spinal segment appears to be a major cause of failure of surgical treatment.

   References Top

Goel A. 'Only fixation' as rationale treatment for spinal canal stenosis. J Craniovertebr Junction Spine 2011;2:55-6.  Back to cited text no. 1
Goel A, Shah A. Facetal distraction as treatment for single- and multilevel cervical spondylotic radiculopathy and myelopathy: A preliminary report. J Neurosurg Spine 2011;14:689-96.  Back to cited text no. 2
Goel A, Shah A, Jadhav M, Nama S. Distraction of facets with intraarticular spacers as treatment for lumbar canal stenosis: Report on a preliminary experience with 21 cases. J Neurosurg Spine 2013;19:672-7.  Back to cited text no. 3
Goel A. Only fixation for cervical spondylosis: Report of early results with a preliminary experience with 6 cases. J Craniovertebr Junction Spine 2013;4:64-8.  Back to cited text no. 4
Goel A. Alternative technique of cervical spinal stabilization employing lateral mass plate and screw and intra-articular spacer fixation. J Craniovertebr Junction Spine 2013;4:56-8.  Back to cited text no. 5
Goel A. Facet distraction spacers for treatment of degenerative disease of the spine: Rationale and an alternative hypothesis of spinal degeneration. J Craniovertebr Junction Spine 2010;1:65-6.  Back to cited text no. 6
Goel A. Facet distraction-arthrodesis technique: Can it revolutionize spinal stabilization methods? J Craniovertebr Junction Spine 2011;2:1-2.  Back to cited text no. 7
Goel A, Dandpat S, Shah A, Rai S, Vutha R. Muscle weakness-related spinal instability is the cause of cervical spinal degeneration and spinal stabilization is the treatment: An experience with 215 cases surgically treated over 7 years. World Neurosurg 2020;140:614-21.  Back to cited text no. 8
Goel A, Shah A, Patni N, Ramdasi R. Immediate postoperative reversal of disc herniation following facetal distraction-fixation surgery: Report of 4 cases. World Neurosurg 2016;94:339-44.  Back to cited text no. 9
Goel A, Dharurkar P, Shah A, Gore S, More S, Ranjan S. Only spinal fixation as treatment of prolapsed cervical intervertebral disc in patients presenting with myelopathy. J Craniovertebr Junction Spine 2017;8:305-10.  Back to cited text no. 10
Goel A, Dharurkar P, Shah A, Gore S, Bakale N, Vaja T. Facetal fixation arthrodesis as treatment of cervical radiculopathy. World Neurosurg 2019;121:e875-e881.  Back to cited text no. 11
Goel A, Vutha R, Shah A, Patil A, Dhar A, Prasad A. Cervical spondylosis in patients presenting with “severe” myelopathy: Analysis of treatment by multisegmental spinal fixation-A case series. J Craniovertebr Junction Spine 2019;10:144-51.  Back to cited text no. 12
Goel A. Role of subaxial spinal and atlantoaxial instability in multisegmental cervical spondylotic myelopathy. Acta Neurochir Suppl 2019;125:71-8.  Back to cited text no. 13
Goel A, Grasso G, Shah A, Rai S, Dandpat S, Vaja T, et al. “Only Spinal Fixation” as surgical treatment of cervical myelopathy related to ossified posterior longitudinal ligament: Review of 52 cases. World Neurosurg 2020;140:556-63.  Back to cited text no. 14
Goel A. Vertical facetal instability: Is it the point of genesis of spinal spondylotic disease? J Craniovertebr Junction Spine 2015;6:47-8.  Back to cited text no. 15
Goel A. Is it necessary to resect osteophytes in degenerative spondylotic myelopathy? J Craniovertebr Junction Spine 2013;4:1-2.  Back to cited text no. 16
Goel A. Is instability the nodal point of pathogenesis for both cervical spondylotic myelopathy and ossified posterior longitudinal ligament? Neurol India 2016;64:837-8.  Back to cited text no. 17
[PUBMED]  [Full text]  
Goel A. Not neural deformation or compression but instability is the cause of symptoms in degenerative spinal disease. J Craniovertebr Junction Spine 2014;5:141-2.  Back to cited text no. 18
Goel A. Beyond radiological imaging: Direct observation and manual physical evaluation of spinal instability. J Craniovertebr Junction Spine 2017;8:88-90.  Back to cited text no. 19
Goel A. Is the term degenerative “spinal canal stenosis” a misnomer? J Craniovertebr Junction Spine 2019;10:75-6.  Back to cited text no. 20
Goel A. Goel's classification of atlantoaxial “facetal” dislocation. J Craniovertebr Junction Spine 2014;5:3-8.  Back to cited text no. 21
Roy-Camille R, Saillant G. Surgery of the cervical spine. 2. Dislocation. Fracture of the articular processes. Nouv Presse Med 1972;1:2484-5.  Back to cited text no. 22
Goel A, Laheri V. Plate and screw fixation for atlanto-axial subluxation. Acta Neurochir (Wien) 1994;129:47-53.  Back to cited text no. 23
Goel A, Desai KI, Muzumdar DP. Atlantoaxial fixation using plate and screw method: A report of 160 treated patients. Neurosurgery 2002;51:1351-6.  Back to cited text no. 24
Goel A, Patil A, Shah A, More S, Vutha R, Ranjan S. Alternative technique of C1-2-3 stabilization-sectioning of muscles attached to C2 spinous process and C2-3 fixation. J Craniovertebr Junction Spine 2020;11:193-7.  Back to cited text no. 25


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